METTL7B Rabbit Polyclonal Antibody

CAT#: TA306680

Rabbit Polyclonal MettL7B Antibody

Product Images

Western blot analysis of MettL7B in Jurkat lysate with MettL7B antibody at (A) 2 and (B) 4 ug/ml.

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  Immunohistochemistry of MettL7B in human spleen tissue with MettL7B antibody at 2.5 ug/ml.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 2 - 4 ug/mL, ICC: 2.5 ug/mL
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: MettL7B antibody was raised against a 13 amino acid peptide near the amino terminus of human MettL7B.
• Formulation: PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: Affinity chromatography purified via peptide column
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: methyltransferase like 7B
• Database Link:
  NP_689850
  Entrez Gene 71664 MouseEntrez Gene 196410 Human
  UniProt ID Q6UX53
• Background: MettL7b belongs to the methyltransferase superfamily. It is a probable methyltransferase. Methyltransferase is a type of transferase enzyme which transfers a methyl group from a donor to an acceptor. Often methylation occurs on nucleic bases in DNA or amino acids in protein structures. DNA methylation is often utilized to silence and regulate genes without changing the original DNA sequence. DNA methylation may be necessary for normal growth from embryonic stages in mammals. When mutant embryonic stem cells lacking the murine DNA methyltransferase gene were introduced to a germline of mice they caused a recessive lethal phenotype. Methylation may also be linked to cancer development as methylation of tumor suppressor genes promotes tumorgenesis and metastasis. This MettL7B antibody is predicted to not cross-react with MettL7A.
• Synonyms: ALDI

Reference Data

• Protein Families: Druggable Genome, Transmembrane