GALNT10 Rabbit Polyclonal Antibody

CAT#: TA306815

Rabbit Polyclonal GALNT10 Antibody

Product Images

Western blot analysis of GALNT10 in SK-N-SH cell lysate with GALNT10 antibody at (A) 1 and (B) 2 ug/ml.

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  Immunohistochemistry of GALNT10 in human brain tissue with GALNT10 antibody at 2.5 ug/ml.

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  Immunofluorescence of GALNT10 in Human Brain cells with GALNT10 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 - 2 ug/mL, ICC: 2.5 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: GALNT10 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human GALNT10.
• Formulation: PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: Affinity chromatography purified via peptide column
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: polypeptide N-acetylgalactosaminyltransferase 10
• Database Link:
  NP_060010
  Entrez Gene 170501 RatEntrez Gene 171212 MouseEntrez Gene 55568 Human
  UniProt ID Q86SR1
• Background: Protein glycosylation is an important biological process that is carried out by a large family of glycosyltransferases that catalyze the synthesis of oligosaccharides and glycoconjugates. Polypeptide GalNAc transferases initiate the synthesis of mucin-type oligosaccharides by transferring GalNAc from UDP-GalNAc to the hydroxyl group of either a serine or threonine residue on the polypeptide acceptor. Polypeptide galactoaminyltransferase 10 (GALNT10) belongs to the polypeptide N-acetylgalactosaminyl-transferase (pp-GalNAc-T) protein family. Following expression in insect cells, recombinant GALNT10 showed significant GalNAcT activity toward mucin-derived peptides, and it utilized both non-glycosylated and glycosylated peptide substrates. GALNT10 mRNA is highly expressed in several distinct hypothalamic, thalamic, and amygdaloid nuclei in mouse brain. At least four isoforms of GALNT10 are known to exist.
• Synonyms: DKFZp586H0623; FLJ00205; FLJ11715; GalNAcT10; pp-GalNAc-T10

Reference Data

• Protein Families: Transmembrane
• Protein Pathways: Metabolic pathways, O-Glycan biosynthesis