C20orf11 (GID8) Rabbit Polyclonal Antibody

CAT#: TA306825

Rabbit Polyclonal TWA1 Antibody

Product Images

Western blot analysis of TWA1 in human brain tissue lysate with TWA1 antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide.

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  Immunohistochemistry of TWA1 in rat brain tissue with TWA1 antibody at 2.5 ug/ml.

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  Immunofluorescence of TWA1 in rat brain tissue with TWA1 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 ug/mL, ICC: 2.5 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: TWA1 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human TWA1.
• Formulation: PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: Affinity chromatography purified via peptide column
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: GID complex subunit 8 homolog
• Database Link:
  NP_060366
  Entrez Gene 76425 MouseEntrez Gene 296466 RatEntrez Gene 54994 Human
  UniProt ID Q9NWU2
• Background: TWA1 was identified through a two hybrid-associated protein screen with RanBPM. TWA1 is well conserved through evolution and is localized within the nucleus. It interacts with RanBP9 and comprises a protein complex with RanBPM and Muskelin. TWA1 was found to possess the LisH-CTLH motif which is detected in proteins involved in microtubule dynamics, cell migration, nucleokinesis and chromosome segregation. These functions overlap with functions suggested for the RanGTPase cycle. Recent findings suggested that there is an as yet uncovered function of the RanGTPase cycle.
• Synonyms: C20orf11; TWA1