PLPP6 Rabbit Polyclonal Antibody

CAT#: TA306886

Rabbit Polyclonal PPAPDC2 Antibody

Product Images

Western blot analysis of PPAPDC2 in Raji cell lysate with PPAPDC2 antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide.

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  Immunofluorescence of PPAPDC2 in Raji cells with PPAPDC2 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: WB: 1 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: PPAPDC2 antibody was raised against a 13 amino acid peptide from near the carboxy terminus human PPAPDC2.
• Formulation: PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: Affinity chromatography purified via peptide column
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: phospholipid phosphatase 6
• Database Link:
  NP_982278
  Entrez Gene 74411 MouseEntrez Gene 619549 RatEntrez Gene 403313 Human
  UniProt ID Q8IY26
• Background: PPAPDC2 is a phosphatase that dephosphorylates Presqualene diphosphate (PSDP) into presqualene monophosphate (PSMP), suggesting that it may have important role in innate immunity. PSDP is a bioactive lipid that rapidly remodels to PSMP upon cell activation. PPAPDC2 displays diphosphate phosphatase activity with a substrate preference for PSDP > FDP > phosphatidic acid. PPAPDC2 activity is independent of Mg2+ and has been identified in activated human neutrophil (PMN) extracts. It is widely expressed in human tissues. Recent studies shows PPAPDC2 is a functional isoprenoid diphosphate phosphatase.
• Synonyms: bA6J24.6; PDP1; PPAPDC2; PSDP

Reference Data

• Protein Families: Transmembrane