MYBPC2 Rabbit Polyclonal Antibody
Other products for "MYBPC2"
Specifications
Product Data | |
Applications | IHC, WB |
Recommended Dilution | WB: 1 - 2 ug/mL, ICC: 5 ug/mL |
Reactivities | Human, Mouse |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | MYBPC2 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human MYBPC2. |
Formulation | PBS containing 0.02% sodium azide. |
Purification | Affinity chromatography purified via peptide column |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Gene Name | myosin binding protein C, fast type |
Database Link | |
Background | Myosin binding protein C (MYBPC) is a component of the thick filament of striated muscle, with the fast-type isoform designated MYBPC2. Both the fast-type and slow-type MYBPC protein contains seven immunoglobulin C2 motifs and three fibronectin type-III repeats. MYBPC2 is typically required for strong contractions and functions under anaerobic conditions. It is more similar to the cardiac isoform (MYBPC3) than to the slow-type isoform (MYBPC1) in terms of pCa50-indexed force development, length-independent cooperativity and length dependent activation. It has been suggested that in cardiac and fast muscle MYBPC2 contributes to an internal load, possibly by binding to actin via its N-terminal region. |
Synonyms | MYBPC; MYBPCF |
Reference Data |
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