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FOXA2 Rabbit Monoclonal Antibody [Clone ID: EPR4466]
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Specifications
| Product Data | |
| Clone Name | EPR4466 |
| Applications | IHC, WB |
| Recommended Dilution | WB: 1:1000 - 1:10000; IHC-P: 1:250 - 1:500; ICC: 1:250 - 1:500 |
| Reactivities | Human, Mouse, Rat |
| Host | Rabbit |
| Isotype | IgG |
| Clonality | Monoclonal |
| Immunogen | A synthetic peptide corresponding to residues in human HNF 3 Beta was used as an immunogen. |
| Formulation | pH: 7.40 Preservative: 0.01% Sodium azide Constituents: 50% Glycerol, 0.05% BSA |
| Purification | Tissue culture supernatant |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Predicted Protein Size | 52 kDa |
| Gene Name | forkhead box A2 |
| Database Link | |
| Background | HNF 3 Beta is a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific proteins such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. HNF 3 Beta has been linked to sporadic cases of maturity-onset diabetes of the young (1). |
| Synonyms | HNF3B; TCF3B |
| Note | Is unsuitable for Flow Cyt or IP. |
| Reference Data | |
| Protein Families | Embryonic stem cells, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Transcription Factors |
| Protein Pathways | Maturity onset diabetes of the young |
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