PIP5KI gamma (PIP5K1C) Rabbit Monoclonal Antibody [Clone ID: MAO-R1]

CAT#: TA307118

Rabbit monoclonal antibody against PIP5K1C(clone MAO-R1)

Product Images

Western blot - PIP5KI gamma antibody [MAO-R1]; All lanes : Anti-PIP5KI gamma antibody [MAO-R1] at 1/1000 dilution.Lane 1 : K562 cell lysate.Lane 2 : Human fetal kidney cell lysate.Lane 3 : C6 cell lysate.Lane 4 : Neuro-2a cell lysate.Lane 5 : 293T cell lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 73 kDa.

Specifications

Product Data

• Clone Name: MAO-R1
• Applications: WB
• Recommended Dilution: WB: 1:1000 - 1:10000; IP: 1:10 - 1:100
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: A full length recombinant mouse PIP5K1C was used as an immunogen.
• Formulation: PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
• Purification: Tissue culture supernatant
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 73 kDa
• Gene Name: phosphatidylinositol-4-phosphate 5-kinase type 1 gamma
• Database Link:
  NP_036530
  Entrez Gene 18717 MouseEntrez Gene 314641 RatEntrez Gene 23396 Human
  UniProt ID O60331
• Background: PIP5K1C is a member of the type I phosphatidylinositol-4-phosphate 5-kinase family of enzymes (1). A similar protein in mice is found in synapses and focal adhesion plaques, and binds the FERM domain of talin through its C-terminus (1). PIP5K1C plays a role in membrane ruffling and assembly of clathrin-coated pits at the synapse (2). It is highly expressed in the forebrain, especially in the cerebellum, hippocampus and cerebral cortex (2).
• Synonyms: LCCS3; PIP5K-GAMMA; PIP5K1-gamma; PIP5Kgamma
• Note: Is unsuitable for Flow Cyt,ICC or IHC-P.

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Endocytosis, Fc gamma R-mediated phagocytosis, Focal adhesion, Inositol phosphate metabolism, Metabolic pathways, Phosphatidylinositol signaling system, Regulation of actin cytoskeleton