Calcitonin (CALCA) Rabbit Monoclonal Antibody [Clone ID: EPR68(2)]

CAT#: TA307516

Rabbit monoclonal antibody against Calcitonin(clone EPR68(2))

Product Images

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Calcitonin antibody [EPR68 (2)]; Immunohistochemical staining of Calcitonin in paraffin embedded Human medullary carcinoma of thyroid gland, using TA307516 at a 1/100 dilution.

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  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-Calcitonin antibody [EPR68 (2)] (TA307516); Immunohistochemical analysis of paraffin embedded Human Papillary carcinoma of thyroid gland tissue using TA307516 showing -ve staining.

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  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-Calcitonin antibody [EPR68 (2)] (TA307516); Immunohistochemical analysis of paraffin embedded Human Prostatic carcinoma tissue using TA307516 showing -ve staining.

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  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-Calcitonin antibody [EPR68 (2)] (TA307516); Immunohistochemical analysis of paraffin embedded normal Human tonsil tissue using TA307516 showing -ve staining.

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  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-Calcitonin antibody [EPR68 (2)] (TA307516); Immunohistochemical analysis of paraffin embedded Human Breast carcinoma tissue using TA307516 showing -ve staining.

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  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-Calcitonin antibody [EPR68 (2)] (TA307516); Immunohistochemical analysis of paraffin embedded Human Glioma tissue using TA307516 showing -ve staining.

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Specifications

Product Data

• Clone Name: EPR68(2)
• Applications: IHC
• Recommended Dilution: IHC-P: 1:100 - 1:250
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: A synthetic peptide corresponding to residues in human Calcitonin was used as an immunogen.
• Formulation: pH: 7.40
  Preservative: 0.01% Sodium azide
  Constituents: 50% Glycerol, 0.05% BSA
• Purification: Tissue culture supernatant
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 15 kDa
• Gene Name: calcitonin related polypeptide alpha
• Database Link:
  NP_001732
  Entrez Gene 796 Human
  UniProt ID P06881
• Background: Calcitonin (Katacalcin) is a 32-amino acid polypeptide hormone that is commonly expressed in the parafollicular or C cells in the thyroid gland. It is also synthesized in a wide variety of other tissues, including the lung and intestinal tract (1). Calcitonin is a potent plasma calcium-lowering peptide; it decreases the level of calcium and phosphate in blood by promoting the incorporation of these ions in bones. Calcitonin staining is used in the identification of C cell proliferative abnormalities, such as C cell hyperplasia and invasive tumors (2). Staining for calcitonin may be used for the identification of a spectrum of C cell proliferative abnormalities ranging from C cell hyperplasia to invasive tumors (e.g. medullary thyroid carcinomas). Calcitonin activitiy might be exhibited in amyloid deposits within the tumor.
• Synonyms: CALC1; CGRP; CGRP-I; CGRP1; CT; KC; PCT
• Note: Is unsuitable for Flow Cyt,ICC/IF,IP or WB.

Reference Data

• Protein Families: Druggable Genome, Secreted Protein