Germany
Japan
United Kingdom
China
FDPS Rabbit Monoclonal Antibody [Clone ID: EPR4628]
Product Images
Other products for "FDPS"
Specifications
| Product Data | |
| Clone Name | EPR4628 |
| Applications | IHC, WB |
| Recommended Dilution | WB: 1:1000 - 1:10000; IHC-P: 1:100 - 1:250; FC: 1:10 - 1:100 |
| Reactivities | Human |
| Host | Rabbit |
| Isotype | IgG |
| Clonality | Monoclonal |
| Immunogen | A synthetic peptide corresponding to residues near the C-terminus of human FDPS was used as an immunogen. |
| Formulation | PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05% |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Gene Name | farnesyl diphosphate synthase |
| Database Link | |
| Background | FDPS is an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption (1). |
| Synonyms | FPPS; FPS; POROK9 |
| Note | Is unsuitable for ICC or IP. |
| Reference Data | |
| Protein Families | Druggable Genome |
| Protein Pathways | Metabolic pathways, Terpenoid backbone biosynthesis |
Documents
| Product Manuals |
| FAQs |
{0} Product Review(s)
0 Product Review(s)
Submit review
Be the first one to submit a review
Product Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.