INPP4A Rabbit Monoclonal Antibody [Clone ID: EP3425(2)]

CAT#: TA307584

Rabbit monoclonal antibody against INPP4A(clone EP3425(2))

Product Images

Western blot - INPP4A antibody [EP3425 (2)]; All lanes : Anti-INPP4A antibody [EP3425 (2)] at 1/1000 dilution.Lane 1 : Fetal brain lysate.Lane 2 : Jurkat cell lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP-labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 110 kDa.Observed band size : 104 kDa.

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  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - INPP4A antibody [EP3425 (2)]; TA307584 at 1/100 dilution staining INPP4A in paraffin-embedded Human brain tissue by Immunohistochemistry.

Specifications

Product Data

• Clone Name: EP3425(2)
• Applications: IHC, WB
• Recommended Dilution: WB: 1:1000 - 1:10000; IHC-P: 1:100 - 1:250; ICC: 1:100 - 1:250
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: A synthetic peptide corresponding to residues in human INPP4A was used as an immunogen.
• Formulation: PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
• Purification: Tissue culture supernatant
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 110 kDa
• Gene Name: inositol polyphosphate-4-phosphatase type I A
• Database Link:
  NP_001127696
  Entrez Gene 80849 RatEntrez Gene 269180 MouseEntrez Gene 3631 Human
  UniProt ID Q96PE3
• Background: INPP4A (Inositol polyphosphate 4-phosphatase), an enzyme of the inositol phosphate signaling pathway, catalyzes the hydrolysis of the 4-position phosphate of inositol 3,4-bisphosphate, inositol 1,3,4-trisphosphate, and phosphatidylinositol 3,4-bisphosphate (1). Hydrolysis of the 4-position phosphate of phosphatidylinositol 3,4-bisphosphate has been implicated in mitogenesis mediated by PDGF receptor, the oxidative burst of neutrophils, and translocation of the glucose transporter to the plasma membrane (2).
• Synonyms: INPP4; TVAS1
• Note: Is unsuitable for Flow Cyt or IP.

Reference Data

• Protein Families: Transmembrane
• Protein Pathways: Inositol phosphate metabolism, Metabolic pathways, Phosphatidylinositol signaling system