DAP Kinase 2 (DAPK2) Rabbit Monoclonal Antibody [Clone ID: EPR1634(2)]

CAT#: TA307795

Rabbit monoclonal antibody against DAPK2(clone EPR1634(2))

Product Images

Western blot - DAP Kinase 2 antibody [EPR1634 (2)]; All lanes : Anti-DAP Kinase 2 antibody [EPR1634 (2)] at 1/1000 dilution.Lane 1 : Human fetal brain lysate.Lane 2 : HepG2 cell lysate.Lane 3 : A431 cell lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 43 kDa.

Specifications

Product Data

• Clone Name: EPR1634(2)
• Applications: WB
• Recommended Dilution: WB: 1:1000 - 1:10000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: A synthetic peptide corresponding to residues on the C-terminus in human DAPK2 was used as an immunogen.
• Formulation: PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: death associated protein kinase 2
• Database Link:
  NP_055141
  Entrez Gene 13143 MouseEntrez Gene 300799 RatEntrez Gene 23604 Human
  UniProt ID Q9UIK4
• Background: Protein kinase termed death-associated protein kinase 2 (DAPK2) dependent on calcium/calmodulin (Ca2+/CaM) contains an N-terminal protein kinase domain followed by a conserved CaM-binding domain with significant homologies to those of DAP kinase, a protein kinase involved in apoptosis. The region of homology spans the catalytic domain and the CaM-regulatory region, whereas the remaining C-terminal part of the protein differs completely from DAP kinase and displays no homology to any known protein. The catalytic domain is also homologous to the recently identified ZIP kinase and to a lesser extent to the catalytic domains of DRAK1 and -2 (1). Overexpression of DAPK2 significantly induced the morphological changes characteristic of apoptosis. Results indicate that DAPK2 is an additional member of DAP kinase family involved in apoptotic signaling (2).
• Synonyms: DRP-1; DRP1
• Note: Is unsuitable for Flow Cyt,ICC,IHC-P or IP.

Reference Data

• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: Bladder cancer, Pathways in cancer