Ferritin Light Chain (FTL) Rabbit Monoclonal Antibody [Clone ID: EPR5260]
Other products for "FTL"
Specifications
Product Data | |
Clone Name | EPR5260 |
Applications | FC, WB |
Recommended Dilution | WB: 1:10000 - 1:50000; IP: 1:10 - 1:100; FC: 1:100 - 1:500 |
Reactivities | Human, Mouse, Rat |
Host | Rabbit |
Isotype | IgG |
Clonality | Monoclonal |
Immunogen | A synthetic peptide corresponding to residues on the C-terminus in human Ferritin was used as an immunogen. This antibody recognizes the light chain only. |
Formulation | PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05% |
Purification | Tissue culture supernatant |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 20 kDa |
Gene Name | ferritin, light polypeptide |
Database Link | |
Background | Ferritin is important in iron homeostasis. It is the main iron-storage protein, composed of two partially homologous subunits, heavy and light chains. Ferritin molecules in cells containing high levels of iron tend to be rich in light chains and may have a long-term storage function, whereas heavy-rich ferritins are more active in iron metabolism (1, 2). Mutations in ferritin cause hereditary hyperferritinemia-cataract syndrome and neuroferritinopathy, associated with inflammation. Elevated levels of ferritin are reported as characteristics of adult-onset Still's disease and hemophagocytic syndrome, also associated with inflammation (3). |
Synonyms | LFTD; NBIA3 |
Note | Is unsuitable for ICC or IHC-P. |
Reference Data | |
Protein Families | Druggable Genome |
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