AKAP12 Rabbit Polyclonal Antibody

CAT#: TA307903

Rabbit polyclonal antibody to AKAP12 (A kinase (PRKA) anchor protein (gravin) 12)

Product Images

Sample (30ug whole cell lysate). A:HeLa S3. 5% SDS PAGE. TA307903 diluted at 1:1000

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  Immunohistochemical analysis of paraffin-embedded serous OVCA, using AKAP12 (TA307903) antibody at 1:100 dilution.

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  Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using AKAP12 (TA307903) antibody at 1:200 dilution.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region within amino acids 1719 and 1782 of AKAP12 (Uniprot ID#Q02952)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 192 kDa
• Gene Name: A-kinase anchoring protein 12
• Database Link:
  NP_005091
  Entrez Gene 9590 Human
  UniProt ID Q02952
• Background: The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq]
• Synonyms: AKAP250; SSeCKS

Reference Data

• Protein Families: Druggable Genome