PEX19 Rabbit Polyclonal Antibody

CAT#: TA307905

Rabbit Polyclonal antibody to PEX19 (peroxisomal biogenesis factor 19)

Product Images

Sample (30 ug of whole cell lysate). A: Raji. B: K562. C: THP-1. D: NCI-H929. 12% SDS PAGE. TA307905 diluted at 1:10000.

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  Sample (50 ug of whole cell lysate). A: mouse liver. 12% SDS PAGE. TA307905 diluted at 1:10000.

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  PEX19 antibody detects PEX19 protein by Western blot analysis. A. 30 ug PC-12 whole cell lysate/extract. B. 30 ug Rat-2 whole cell lysate/extract. 10 % SDS-PAGE. PEX19 antibody (TA307905) dilution: 1:1000

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  Immunohistochemical analysis of paraffin-embedded SW480 xenograft, using PEX19 (TA307905) antibody at 1:500 dilution.

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  Confocal immunofluorescence analysis (Olympus FV10i) of methanol-fixed HeLa, using PEX19 (TA307905) antibody (Green) at 1:500 dilution. Alpha-tubulin filaments were labeled with anti-alpha tubulin antibody (Red) at 1:2000.

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Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:1000-1:10000
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 299 of PEX19 (Uniprot ID#P40855)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 33 kDa
• Gene Name: peroxisomal biogenesis factor 19
• Database Link:
  NP_001124511
  Entrez Gene 19298 MouseEntrez Gene 5824 Human
  UniProt ID P40855
• Background: This gene is necessary for early peroxisomal biogenesis. It acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause Zellweger syndrome (ZWS). [provided by RefSeq]
• Synonyms: 33kD; D1S2223E; FLJ55296; HK33; housekeeping gene; OTTHUMP00000031848; peroxisomal biogenesis factor 19; peroxisomal farnesylated protein; PMP1; PMPI; PXF; PXMP1

Reference Data

• Protein Families: Druggable Genome