TRIM37 Rabbit Polyclonal Antibody

CAT#: TA307938

Rabbit Polyclonal antibody to TRIM37 (tripartite motif-containing 37)

Product Images

Sample (30 ug of whole cell lysate). A: A431. B: HeLa. C: HepG2. 7.5% SDS PAGE. TA307938 diluted at 1:1000.

• 

  Immunohistochemical analysis of paraffin-embedded U87 xenograft, using TRIM37 (TA307938) antibody at 1:500 dilution.

• 

  Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using TRIM37 (TA307938) antibody at 1:200 dilution.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region within amino acids 902 and 964 of TRIM37 (Uniprot ID#O94972)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 108 kDa
• Gene Name: tripartite motif containing 37
• Database Link:
  NP_001005207
  Entrez Gene 4591 Human
• Background: This gene encodes a member of the tripartite motif (TRIM) family, whose members are involved in diverse cellular functions such as developmental patterning and oncogenesis. The TRIM motif includes zinc-binding domains, a RING finger region, a B-box motif and a coiled-coil domain. The RING finger and B-box domains chelate zinc and might be involved in protein-protein and/or protein-nucleic acid interactions. The gene mutations are associated with mulibrey (muscle-liver-brain-eye) nanism, an autosomal recessive disorder that involves several tissues of mesodermal origin. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq]
• Synonyms: MUL; POB1; TEF3
• Note: Seq homology of immunogen across species: Rhesus Monkey (92%), Bovine (92%)

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Ubiquitin mediated proteolysis