CSB (ERCC6) Rabbit Polyclonal Antibody

CAT#: TA307948

Rabbit polyclonal antibody to CSB (excision repair cross-complementing rodent repair deficiency, complementation group 6)

Product Images

CSB antibody [N2C1], Internal detects CSB protein by western blot analysis. A. 30 ug 294T whole cell lysate/extract. B. 30 ug A432 whole cell lysate/extract. C. 31 ug HeLa whole cell lysate/extract. D. 30 ug HepG3 whole cell lysate/extract. 5 % SDS-PAGE.

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  CSB antibody [N2C1], Internal detects CSB protein at nucleus on mouse muscle by immunohistochemical analysis. Sample: Paraffin-embedded mouse muscle. CSB antibody [N2C1], Internal (TA307948) dilution: 1:500.

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  CSB antibody [N2C1], Internal detects CSB protein at nucleus on rat hind brain by immunohistochemical analysis. Sample: Paraffin-embedded rat hind brain. CSB antibody [N2C1], Internal (TA307948) dilution: 1:500.

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  CSB antibody [N2C1], Internal detects CSB protein at nucleus by immunofluorescent analysis. Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: CSB protein stained by CSB antibody [N2C1], Internal (TA307948) diluted at 1:500. Blu

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 346 and 766 of CSB (Uniprot ID#Q03468)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 168 kDa
• Gene Name: ERCC excision repair 6, chromatin remodeling factor
• Database Link:
  NP_000115
  Entrez Gene 2074 Human
  UniProt ID Q03468
• Background: This gene encodes a DNA-binding protein that is important in transcription-coupled excision repair. The protein has ATP-stimulated ATPase activity; there are contradictory publications reporting presence or absence of helicase activity. The protein appears to interact with several transcription and excision repair proteins, and may promote complex formation at repair sites. Mutations in this gene result in Cockayne syndrome type B. [provided by RefSeq]
• Synonyms: ARMD5; CKN2; COFS; COFS1; CSB; RAD26; UVSS1

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Nucleotide excision repair