COX6A2 Rabbit Polyclonal Antibody

CAT#: TA307955

Rabbit Polyclonal antibody to COX6A2 (cytochrome c oxidase subunit VIa polypeptide 2)

Product Images

Sample (30 ug of whole cell lysate). A:Raji. 12% SDS PAGE. TA307955 diluted at 1:500

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  Immunohistochemical analysis of paraffin-embedded SCC4 xenograft, using COX6A2 (TA307955) antibody at 1:100 dilution.

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  COX6A2 antibody [N3C3] detects COX6A2 protein at mitochondria by immunofluorescent analysis. Sample: SK-N-SH cells were fixed in 2% paraformaldehyde/culture medium at 37°C for 30min. Green: COX6A2 protein stained by COX6A2 antibody [N3C3] (TA307955) dilu

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region within amino acids 34 and 97 of COX6A2 (Uniprot ID#Q02221)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 11 kDa
• Gene Name: cytochrome c oxidase subunit 6A2
• Database Link:
  NP_005196
  Entrez Gene 12862 MouseEntrez Gene 25278 RatEntrez Gene 1339 Human
  UniProt ID Q02221
• Background: Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 2 (heart/muscle isoform) of subunit VIa, and polypeptide 2 is present only in striated muscles. Polypeptide 1 (liver isoform) of subunit VIa is encoded by a different gene, and is found in all non-muscle tissues. These two polypeptides share 66% amino acid sequence identity. [provided by RefSeq]
• Synonyms: COX6AH; COXVIAH
• Note: Seq homology of immunogen across species: Mouse (93%), Rat (86%), Rhesus Monkey (100%)

Reference Data

• Protein Pathways: Alzheimer's disease, Cardiac muscle contraction, Huntington's disease, Metabolic pathways, Oxidative phosphorylation, Parkinson's disease