CROT Rabbit Polyclonal Antibody

CAT#: TA307959

Rabbit Polyclonal antibody to CROT (carnitine O-octanoyltransferase)

Product Images

Sample (50 ug of whole cell lysate). A: mouse liver. 7.5% SDS PAGE. TA307959 diluted at 1:1000.

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  Sample (30 ug of whole cell lysate). A: 293T. B: A431. 7.5% SDS PAGE. COT antibody. TA307959 diluted at 1:1000.

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  Immunohistochemical analysis of paraffin-embedded Ca922 xenograft, using CROT (TA307959) antibody at 1:100 dilution.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: IHC:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 140 and 462 of CROT (Uniprot ID#Q9UKG9)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 70 kDa
• Gene Name: carnitine O-octanoyltransferase
• Database Link:
  NP_001137407
  Entrez Gene 74114 MouseEntrez Gene 54677 Human
  UniProt ID Q9UKG9
• Background: This gene encodes a member of the carnitine/choline acetyltransferase family. The encoded protein converts 4,8-dimethylnonanoyl-CoA to its corresponding carnitine ester. This transesterification occurs in the peroxisome and is necessary for transport of medium- and long- chain acyl-CoA molecules out of the peroxisome to the cytosol and mitochondria. The protein thus plays a role in lipid metabolism and fatty acid beta-oxidation. Alternatively spliced transcript variants have been described.
• Synonyms: COT
• Note: Seq homology of immunogen across species: mouse (80%)

Reference Data

• Protein Families: Druggable Genome