EPS8 Rabbit Polyclonal Antibody

CAT#: TA307988

Rabbit polyclonal antibody to EPS8 (epidermal growth factor receptor pathway substrate 8)

Product Images

Sample (30 ug of whole cell lysate). A: H1299. B: Hela. 7.5% SDS PAGE. EPS8 antibody. TA307988 diluted at 1:1000.

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  EPS8 antibody [C3], C-term detects EPS8 protein at cytosol and nucleus on human breast carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded human breast carcinoma. EPS8 antibody [C3], C-term (TA307988) dilution: 1:500.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: IHC:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region within amino acids 761 and 822 of EPS8 (Uniprot ID#Q12929)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 92 kDa
• Gene Name: epidermal growth factor receptor pathway substrate 8
• Database Link:
  NP_004438
  Entrez Gene 13860 MouseEntrez Gene 2059 Human
  UniProt ID Q12929
• Background: This gene encodes a member of the EPS8 family. This protein contains one PH domain and one SH3 domain. It functions as part of the EGFR pathway, though its exact role has not been determined. Highly similar proteins in other organisms are involved in the transduction of signals from Ras to Rac and growth factor-mediated actin remodeling. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq]
• Synonyms: DFNB102
• Note: Seq homology of immunogen across species: Mouse (100%), Xenopus laevis (92%), Xenopus Tropicalis (92%), Rhesus Monkey (100%)

Reference Data

• Protein Families: Druggable Genome