SPG7 Rabbit Polyclonal Antibody

CAT#: TA308134

Rabbit Polyclonal antibody to SPG7 (spastic paraplegia 7 (pure and complicated autosomal recessive))

Product Images

Sample (50 ug of whole cell lysate). A: Mouse brain. 7.5% SDS PAGE. TA308134 diluted at 1:1000.

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  Sample (30 ug of whole cell lysate). A: 293T. 7.5% SDS PAGE. TA308134 diluted at 1:1000.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB:1:500-1:3000
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 384 and 598 of SPG7 (Uniprot ID#Q9UQ90)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 88 kDa
• Gene Name: SPG7, paraplegin matrix AAA peptidase subunit
• Database Link:
  NP_955399
  Entrez Gene 234847 MouseEntrez Gene 6687 Human
  UniProt ID Q9UQ90
• Background: This gene encodes a nuclear-encoded mitochondrial metalloprotease protein that is a member of the AAA (ATPases associated with a variety of cellular activities) protein family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. Two transcript variants encoding distinct isoforms have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 7. [provided by RefSeq]
• Synonyms: CAR; CMAR; PGN; SPG5C
• Note: Seq homology of immunogen across species: Chicken (85%), Bovine (90%)

Reference Data

• Protein Families: Protease, Transmembrane