COX5B Rabbit Polyclonal Antibody

CAT#: TA308206

Rabbit Polyclonal antibody to COX5B (cytochrome c oxidase subunit Vb)

Product Images

Sample (30 ug of whole cell lysate). A:Hep G2. 15% SDS PAGE. TA308206 diluted at 1:1000

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  Immunohistochemical analysis of paraffin-embedded H441 xenograft, using COX5B (TA308206) antibody at 1:100 dilution.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: IHC:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 129 of COX5B (Uniprot ID#P10606)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Affinity purified by Protein A.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 14 kDa
• Gene Name: cytochrome c oxidase subunit 5B
• Database Link:
  NP_001853
  Entrez Gene 12859 MouseEntrez Gene 94194 RatEntrez Gene 474567 DogEntrez Gene 1329 Human
  UniProt ID P10606
• Background: Cytochrome C oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit Vb of the human mitochondrial respiratory chain enzyme. [provided by RefSeq]
• Synonyms: COXVB
• Note: Seq homology of immunogen across species: Mouse (85%), Dog (83%), Pig (83%), Rat (82%), Bovine (84%)

Reference Data

• Protein Pathways: Alzheimer's disease, Cardiac muscle contraction, Huntington's disease, Metabolic pathways, Oxidative phosphorylation, Parkinson's disease