GLB1 Rabbit Polyclonal Antibody

CAT#: TA308238

Rabbit polyclonal antibody to beta-Gal (galactosidase, beta 1)

Product Images

Sample (30 ug of whole cell lysate). A: H1299. 7.5% SDS PAGE. TA308238 diluted at 1:1000.

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  beta-Gal antibody [N2C3] detects beta-Gal protein at cytosol on human ovarian carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded human ovarian carcinoma. beta-Gal antibody [N2C3] (TA308238) dilution: 1:500.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: IHC:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 166 and 677 of beta-Gal (Uniprot ID#P16278)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 76 kDa
• Gene Name: galactosidase beta 1
• Database Link:
  NP_001129074
  Entrez Gene 403873 DogEntrez Gene 2720 Human
  UniProt ID P16278
• Background: This gene encodes beta-galactosidase-1, a lysosomal enzyme that hydrolyzes the terminal beta-galactose from ganglioside substrates and other glycoconjugates. Defects in this gene are the cause of GM1-gangliosidosis and Morquio B syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
• Synonyms: EBP; ELNR1; MPS4B
• Note: Seq homology of immunogen across species: Dog (82%), Cat (81%)

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Galactose metabolism, Glycosaminoglycan degradation, Glycosphingolipid biosynthesis - ganglio series, Lysosome, Metabolic pathways, Other glycan degradation, Sphingolipid metabolism