LHCGR Rabbit Polyclonal Antibody

CAT#: TA308266

Rabbit polyclonal antibody to LHR (luteinizing hormone/choriogonadotropin receptor)

Product Images

Sample (30 ug of whole cell lysate). A: H1299. 7.5% SDS PAGE. LHR antibody. TA308266 diluted at 1:1000.

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  LHR antibody [C3], C-term detects LHR protein at cytosol on human lung carcinoma by immunohistochemical analysis. Sample: LHR antibody [C3], C-term (TA308266) dilution: 1:250.

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  Immunohistochemical analysis of paraffin-embedded Gastric ca, using LHR (TA308266) antibody at 1:500 dilution.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: IHC:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region within amino acids 622 and 699 of LHR (Uniprot ID#P22888)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 79 kDa
• Gene Name: luteinizing hormone/choriogonadotropin receptor
• Database Link:
  NP_000224
  Entrez Gene 25477 RatEntrez Gene 3973 Human
  UniProt ID P22888
• Background: This gene encodes the receptor for both luteinizing hormone and choriogonadotropin. This receptor belongs to the G-protein coupled receptor 1 family, and its activity is mediated by G proteins which activate adenylate cyclase. Mutations in this gene result in disorders of male secondary sexual character development, including familial male precocious puberty, also known as testotoxicosis, hypogonadotropic hypogonadism, Leydig cell adenoma with precocious puberty, and male pseudohermaphtoditism with Leydig cell hypoplasia. [provided by RefSeq]
• Synonyms: CG-R; CGR; HHG; LCGR; LGR2; LH; LHR; LHRHR; LSH-R; ULG5
• Note: Seq homology of immunogen across species: Rat (85%)

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Calcium signaling pathway, Neuroactive ligand-receptor interaction