NKG2D (KLRK1) Rabbit Polyclonal Antibody

CAT#: TA308267

Rabbit polyclonal antibody to CD314 (killer cell lectin-like receptor subfamily K, member 1)

Product Images

NKG2D antibody [N3C2], Internal detects NKG2D protein at cytosol on human lung carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded human lung carcinoma. NKG2D antibody [N3C2], Internal (TA308267) dilution: 1:250.

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: IHC:1:100-1:1000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region within amino acids 86 and 177 of NKG2D
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 25 kDa
• Gene Name: killer cell lectin like receptor K1
• Database Link:
  NP_031386
  Entrez Gene 22914 Human
• Background: Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. This gene encodes a member of the NKG2 family, and the encoded transmembrane protein is characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed in NK cells. [provided by RefSeq]
• Synonyms: CD314; D12S2489E; KLR; NKG2-D; NKG2D

Reference Data

• Protein Families: Transmembrane
• Protein Pathways: Natural killer cell mediated cytotoxicity