IL22 RA2 (IL22RA2) Rabbit Polyclonal Antibody

CAT#: TA308336

Rabbit polyclonal antibody to IL-22R alpha 2 (interleukin 22 receptor, alpha 2)

Product Images

Sample (30 ug of whole cell lysate). A:HeLa S3. 12% SDS PAGE. TA308336 diluted at 1:200

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  IL22 Receptor alpha 2 antibody detects IL22RA2 protein at cytosol on PC14 xenograft by immunohistochemical analysis. Sample: Paraffin-embedded PC14 xenograft. IL22 Receptor alpha 2 antibody (TA308336) dilution: 1:250.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: IHC:1:100-1:1000; WB:1:100-1:1000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 218 of IL22 Receptor alpha 2
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 27 kDa
• Gene Name: interleukin 22 receptor subunit alpha 2
• Database Link:
  NP_851827
  Entrez Gene 116379 Human
  UniProt ID Q969J5
• Background: The protein encoded by this gene is a soluble class II cytokine receptor. This protein has been shown to specifically bind to interleukin 22 (IL22), block the interaction of IL22 with its cell surface receptor, and thus inhibit IL22 activity. This protein functions as an IL22 antagonist, and may be important in the regulation of inflammatory response. Three alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq]
• Synonyms: CRF2-10; CRF2-S1; CRF2X; IL-22BP; IL-22R-alpha-2; IL-22RA2; ZCYTOR16

Reference Data

• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway