FBXO2 Rabbit Polyclonal Antibody

CAT#: TA308339

Rabbit Polyclonal antibody to FBXO2 (F-box protein 2)

Product Images

Sample (30 ug of whole cell lysate). A: H1299. 12% SDS PAGE. TA308339 diluted at 1:1000.

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  Immunohistochemical analysis of paraffin-embedded Adrenal gland tumor, using FBXO2 (TA308339) antibody at 1:100 dilution.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: IHC:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region within amino acids 234 and 296 of FBXO2 (Uniprot ID#Q9UK22)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 33 kDa
• Gene Name: F-box protein 2
• Database Link:
  NP_036300
  Entrez Gene 85273 RatEntrez Gene 230904 MouseEntrez Gene 26232 Human
  UniProt ID Q9UK22
• Background: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. This protein is highly similar to the rat NFB42 (neural F Box 42 kDa) protein which is enriched in the nervous system and may play a role in maintaining neurons in a postmitotic state. [provided by RefSeq]
• Synonyms: FBG1; Fbs1; FBX2; NFB42; OCP1
• Note: Seq homology of immunogen across species: Mouse (100%), Rat (100%), Bovine (100%)

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Ubiquitin mediated proteolysis