TCP1 beta (CCT2) Rabbit Polyclonal Antibody

CAT#: TA308346

Rabbit Polyclonal antibody to TCP1 beta (chaperonin containing TCP1, subunit 2 (beta))

Product Images

Sample (50 ug of whole cell lysate). A: Mouse brain. 7.5% SDS PAGE. TA308346 diluted at 1:1000.

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  Sample (30 ug of whole cell lysate). A: Hep G2. B: Raji. 7.5% SDS PAGE. TA308346 diluted at 1:1000.

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  Immunohistochemical analysis of paraffin-embedded SW480 xenograft, using TCP1 beta (TA308346) antibody at 1:100 dilution.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: IHC:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 277 and 503 of TCP1 beta (Uniprot ID#P78371)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 58 kDa
• Gene Name: chaperonin containing TCP1 subunit 2
• Database Link:
  NP_006422
  Entrez Gene 12461 MouseEntrez Gene 10576 Human
  UniProt ID P78371
• Background: This gene encodes a molecular chaperone that is member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of the gene described in this record have been observed but have not been thoroughly characterized. [provided by RefSeq]
• Synonyms: 99D8.1; CCT-beta; CCTB; HEL-S-100n; PRO1633; TCP-1-beta
• Note: Seq homology of immunogen across species: Pig (100%), Rabbit (100%), Rhesus Monkey (100%), Chimpanzee (100%)

Reference Data

• Protein Families: Druggable Genome