RGS17 Rabbit Polyclonal Antibody

CAT#: TA308384

Rabbit Polyclonal antibody to RGS17 (regulator of G-protein signaling 17)

Product Images

Sample (30 ug of whole cell lysate). A: Non-transfected 293T lysates. B: RGS17 transfected 293T lysates. 12% SDS PAGE. TA308384 diluted at 1:5000.

• 

  Immunofluorescence analysis of paraformaldehyde-fixed A431, using RGS17 (TA308384) antibody at 1:200 dilution.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: ICC/IF:1:100-1:1000; WB:1:1000-1:10000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region within amino acids 148 and 210 of RGS17 (Uniprot ID#Q9UGC6)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 24 kDa
• Gene Name: regulator of G-protein signaling 17
• Database Link:
  NP_036551
  Entrez Gene 26575 Human
  UniProt ID Q9UGC6
• Background: This gene encodes a member of the regulator of G-protein signaling family. This protein contains a conserved, 120 amino acid motif called the RGS domain and a cysteine-rich region. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. [provided by RefSeq]
• Synonyms: hRGS17; RGS-17; RGSZ2

Reference Data

• Protein Families: Druggable Genome