CD1 (CD1D) Rabbit Polyclonal Antibody

CAT#: TA308385

Rabbit polyclonal antibody to CD1D (CD1D molecule)

Product Images

Sample (30 ug of whole cell lysate). A: Raji. 10% SDS PAGE. CD1D antibody. TA308385 diluted at 1:1000.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB:1:500-1:3000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 56 and 317 of CD1D (Uniprot ID#P15813)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 38 kDa
• Gene Name: CD1d molecule
• Database Link:
  NP_001757
  Entrez Gene 613268 MonkeyEntrez Gene 912 Human
  UniProt ID P15813
• Background: This gene encodes a divergent member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail. [provided by RefSeq]
• Synonyms: CD1A; R3; R3G1
• Note: Seq homology of immunogen across species: Monkey (92%)

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Hematopoietic cell lineage