Glutathione S Transferase theta 1 (GSTT1) Rabbit Polyclonal Antibody

CAT#: TA308416

Rabbit polyclonal antibody to GSTT1 (glutathione S-transferase theta 1)

Product Images

GSTT1 antibody detects GSTT1 protein by Western blot analysis. A. 50 ug rat liver lysate/extract. 12 % SDS-PAGE. GSTT1 antibody (TA308416) dilution: 1:500

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  Sample (30 ug of whole cell lysate). A: Hep G2. 10% SDS PAGE. TA308416 diluted at 1:1000

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  GSTT1 antibody detects GSTT1 protein by Western blot analysis. A. 50 ug mouse spleen lysate/extract. 12 % SDS-PAGE. GSTT1 antibody (TA308416) dilution: 1:500

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  GSTT1 antibody detects GSTT1 protein at cytosol on gastric carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded hepatoma. GSTT1 antibody (TA308416) dilution: 1:500.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: IHC:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 240 of GSTT1 (Uniprot ID#P30711)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 27 kDa
• Gene Name: glutathione S-transferase theta 1
• Database Link:
  NP_000844
  Entrez Gene 2952 Human
  UniProt ID P30711
• Background: Glutathione S-transferase (GST) theta 1 (GSTT1) is a member of a superfamily of proteins that catalyze the conjugation of reduced glutathione to a variety of electrophilic and hydrophobic compounds. Human GSTs can be divided into five main classes: alpha, mu, pi, theta, and zeta. The theta class includes GSTT1 and GSTT2. The GSTT1 and GSTT2 share 55% amino acid sequence identity and both of them were claimed to have an important role in human carcinogenesis. The GSTT1 gene is located approximately 50kb away from the GSTT2 gene. The GSTT1 and GSTT2 genes have a similar structure, being composed of five exons with identical exon/intron boundaries. [provided by RefSeq]
• Synonyms: glutathione S-transferase theta 1

Reference Data

• Protein Pathways: Drug metabolism - cytochrome P450, Glutathione metabolism, Metabolism of xenobiotics by cytochrome P450