NAT1 Rabbit Polyclonal Antibody

CAT#: TA308422

Rabbit Polyclonal antibody to NAT1 (N-acetyltransferase 1 (arylamine N-acetyltransferase))

Product Images

Sample (30 ug of whole cell lysate). A: Hela. 12% SDS PAGE. TA308422 diluted at 1:1000.

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  Immunohistochemical analysis of paraffin-embedded A549 xenograft, using NAT1 (TA308422) antibody at 1:100 dilution.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: IHC:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 187 of NAT1 (Uniprot ID#P18440)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 34 kDa
• Gene Name: N-acetyltransferase 1 (arylamine N-acetyltransferase)
• Database Link:
  NP_000653
  Entrez Gene 9 Human
  UniProt ID P18440
• Background: This gene is one of two arylamine N-acetyltransferase (NAT) genes in the human geneome, and is orthologous to the mouse and rat Nat2 genes. The enzyme encoded by this gene catalyzes the transfer of an acetyl group from acetyl-CoA to various arylamine and hydrazine substrates. This enzyme helps metabolize drugs and other xenobiotics, and functions in folate catabolism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
• Synonyms: AAC1; MNAT; NAT-1; NATI
• Note: Seq homology of immunogen across species: Bovine (83%)

Reference Data

• Protein Pathways: Caffeine metabolism, Drug metabolism - other enzymes, Metabolic pathways