STIP1 Rabbit Polyclonal Antibody

CAT#: TA308465

Rabbit Polyclonal antibody to STIP1 (stress-induced-phosphoprotein 1)


USD 415.00

In Stock*

Size
    • 100 ul

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Specifications

Product Data
Applications IF, IHC, WB
Recommended Dilution ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:1000-1:10000
Reactivities Human, Mouse
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Recombinant fragment corresponding to a region within amino acids 1 and 300 of STIP1 (Uniprot ID#P31948)
Formulation 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Concentration lot specific
Purification Purified by antigen-affinity chromatography.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Predicted Protein Size 63 kDa
Gene Name stress induced phosphoprotein 1
Background STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A; MIM 140550) and HSP90 (see HSP90AA1; MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 [PubMed 16100115]). [supplied by OMIM]
Synonyms HEL-S-94n; HOP; IEF-SSP-3521; P60; STI1; STI1L
Reference Data
Protein Families Stem cell - Pluripotency
Protein Pathways Prion diseases

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