HRH3 Rabbit Polyclonal Antibody

CAT#: TA308494

Rabbit polyclonal antibody to Histamine H3 Receptor (histamine receptor H3)

Product Images

Sample (30 ug of whole cell lysate). A: A431. B: H1299. 10% SDS PAGE. TA308494 diluted at 1:1000.

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  Immunohistochemical analysis of paraffin-embedded HeLa xenograft, using Histamine H3 Receptor (TA308494) antibody at 1:500 dilution.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: IHC:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region within amino acids 293 and 387 of Histamine H3 Receptor (Uniprot ID#Q9Y5N1)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Affinity purified by Protein A.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 49 kDa
• Gene Name: histamine receptor H3
• Database Link:
  NP_009163
  Entrez Gene 85268 RatEntrez Gene 99296 MouseEntrez Gene 11255 Human
  UniProt ID Q9Y5N1
• Background: Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene encodes one of the histamine receptors (H3) which belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and can regulate neurotransmitter release. This receptor can also increase voltage-dependent calcium current in smooth muscles and innervates the blood vessels and the heart in cardiovascular system. [provided by RefSeq]
• Synonyms: GPCR97; HH3R
• Note: Seq homology of immunogen across species: Mouse (87%), Rat (87%), Rabbit (85%), Rhesus Monkey (100%), Guinea pig (87%)

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Neuroactive ligand-receptor interaction