Prostaglandin dehydrogenase 1 (HPGD) Rabbit Polyclonal Antibody

CAT#: TA308509

Rabbit Polyclonal antibody to 15-PGDH (hydroxyprostaglandin dehydrogenase 15-(NAD))

Product Images

Sample (30ug whole cell lysate). A:Raji. 12% SDS PAGE. TA308509 diluted at 1:1000

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  Immunohistochemical analysis of paraffin-embedded MDA-MB-468 xenograft, using 15-PGDH (TA308509) antibody at 1:500 dilution.

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  Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using 15-PGDH (TA308509) antibody at 1:200 dilution.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region within amino acids 205 and 266 of 15-PGDH (Uniprot ID#P15428)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 29 kDa
• Gene Name: hydroxyprostaglandin dehydrogenase 15-(NAD)
• Database Link:
  NP_001139288
  Entrez Gene 3248 Human
  UniProt ID P15428
• Background: This gene encodes a member of the short-chain nonmetalloenzyme alcohol dehydrogenase protein family. The encoded enzyme is responsible for the metabolism of prostaglandins, which function in a variety of physiologic and cellular processes such as inflammation. Mutations in this gene result in primary autosomal recessive hypertrophic osteoarthropathy and cranioosteoarthropathy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
• Synonyms: 15-PGDH; PGDH; PGDH1; PHOAR1; SDR36C1
• Note: Seq homology of immunogen across species: Pig (83%)

Reference Data

• Protein Families: Druggable Genome