UBA1 Rabbit Polyclonal Antibody

CAT#: TA308512

Rabbit Polyclonal antibody to UBE1 (ubiquitin-like modifier activating enzyme 1)

Specifications

Product Data

• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 753 and 1006 of UBE1 (Uniprot ID#P22314)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 118 kDa
• Gene Name: ubiquitin like modifier activating enzyme 1
• Database Link:
  NP_003325
  Entrez Gene 22201 MouseEntrez Gene 7317 Human
• Background: The protein encoded by this gene catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation. This gene complements an X-linked mouse temperature-sensitive defect in DNA synthesis, and thus may function in DNA repair. It is part of a gene cluster on chromosome Xp11.23. Alternatively spliced transcript variants that encode the same protein have been described. [provided by RefSeq]
• Synonyms: A1S9; A1S9T; A1ST; AMCX1; CFAP124; GXP1; POC20; SMAX2; UBA1A; UBE1; UBE1X
• Note: Seq homology of immunogen across species: Human (100%)

Reference Data

• Protein Pathways: Parkinson's disease, Ubiquitin mediated proteolysis