Livin (BIRC7) Rabbit Polyclonal Antibody

CAT#: TA308543

Rabbit polyclonal antibody to ML-IAP (baculoviral IAP repeat-containing 7)

Product Images

Livin antibody detects BIRC7 protein by Western blot analysis. A. 30 ug 293T whole cell lysate/extract. B. 30 ug A431 whole cell lysate/extract. C. 30 ug HepG2 whole cell lysate/extract. 12 % SDS-PAGE. Livin antibody (TA308543) dilution: 1:500

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  Immunohistochemical analysis of paraffin-embedded Cal27 xenograft, using ML-IAP (TA308543) antibody at 1:100 dilution.

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  Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using ML-IAP (TA308543) antibody at 1:200 dilution.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 241 of Livin (Uniprot ID#Q96CA5)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 33 kDa
• Gene Name: baculoviral IAP repeat containing 7
• Database Link:
  NP_071444
  Entrez Gene 79444 Human
  UniProt ID Q96CA5
• Background: The protein encoded by this gene is a member of the family of inhibitor of apoptosis proteins (IAP) and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Two transcript variants encoding different isoforms have been found for this gene. The two isoforms have different antiapoptotic properties, with isoform alpha protecting cells from apoptosis induced by staurosporine and isoform b protecting cells from apoptosis induced by etoposide. [provided by RefSeq]
• Synonyms: KIAP; LIVIN; ML-IAP; MLIAP; RNF50

Reference Data

• Protein Families: Druggable Genome