Ornithine Decarboxylase (ODC1) Rabbit Polyclonal Antibody

CAT#: TA308547

Rabbit polyclonal antibody to ODC (ornithine decarboxylase 1)

Product Images

Sample (30 ug of whole cell lysate). A: Molt-4. 10% SDS PAGE. TA308547 diluted at 1:1000.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB:1:500-1:3000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 180 and 461 of ODC (Uniprot ID#P11926)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 51 kDa
• Gene Name: ornithine decarboxylase 1
• Database Link:
  NP_002530
  Entrez Gene 18263 MouseEntrez Gene 24609 RatEntrez Gene 695625 MonkeyEntrez Gene 4953 Human
  UniProt ID P11926
• Background: This gene encodes the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins. Originally localized to both chromosomes 2 and 7, the gene encoding this enzyme has been determined to be located on 2p25, with a pseudogene located on 7q31-qter. [provided by RefSeq]
• Synonyms: ODC
• Note: Seq homology of immunogen across species: Mouse (91%), Chicken (85%), Monkey (98%), Rat (91%), Bovine (93%)

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Arginine and proline metabolism, Glutathione metabolism, Metabolic pathways