FBXL12 Rabbit Polyclonal Antibody

CAT#: TA308590

Rabbit Polyclonal antibody to FBXL12 (F-box and leucine-rich repeat protein 12)

Product Images

Sample (30 ug of whole cell lysate). A: NIH-3T3. 12% SDS PAGE. FBXL12 antibody. TA308590 diluted at 1:1000.

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  Sample (30 ug of whole cell lysate). A: Hep G2. 10% SDS PAGE. TA308590 diluted at 1:1000

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  Immunohistochemical analysis of paraffin-embedded SW480 xenograft, using FBXL12 (TA308590) antibody at 1:500 dilution.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: IHC:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region within amino acids 265 and 326 of FBXL12 (Uniprot ID#Q9NXK8)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 37 kDa
• Gene Name: F-box and leucine-rich repeat protein 12
• Database Link:
  NP_060173
  Entrez Gene 30843 MouseEntrez Gene 313782 RatEntrez Gene 54850 Human
  UniProt ID Q9NXK8
• Background: Members of the F-box protein family, such as FBXL12, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]). [supplied by OMIM]
• Synonyms: Fbl12
• Note: Seq homology of immunogen across species: Rat (100%), Bovine (92%)

Reference Data

• Protein Families: Druggable Genome