ULK2 Rabbit Polyclonal Antibody

CAT#: TA308622

Rabbit Polyclonal antibody to ULK2 (unc-51-like kinase 2 (C. elegans))

Product Images

Sample (30 ug of whole cell lysate). A: NT2D1. B: PC-3. 7.5% SDS PAGE. TA308622 diluted at 1:1000.

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  Sample (30 ug of whole cell lysate). A: NIH-3T3. 7.5% SDS PAGE. TA308622 diluted at 1:1000.

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  Immunohistochemical analysis of paraffin-embedded MCF7 xenograft, using ULK2 (TA308622) antibody at 1:500 dilution.

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  Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using ULK2 (TA308622) antibody at 1:200 dilution.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 693 and 968 of ULK2 (Uniprot ID#Q8IYT8)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 113 kDa
• Gene Name: unc-51 like autophagy activating kinase 2
• Database Link:
  NP_001136082
  Entrez Gene 9706 Human
  UniProt ID Q8IYT8
• Background: This gene encodes a protein that is similar to a serine/threonine kinase in C. elegans which is involved in axonal elongation. The structure of this protein is similar to the C. elegans protein in that both proteins have an N-terminal kinase domain, a central proline/serine rich (PS) domain, and a C-terminal (C) domain. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq]
• Synonyms: ATG1B; Unc51.2

Reference Data

• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: mTOR signaling pathway, Regulation of autophagy