HOMER3 Rabbit Polyclonal Antibody

CAT#: TA308627

Rabbit polyclonal antibody to Homer-3 (homer homolog 3 (Drosophila))

Product Images

Sample (30 ug of whole cell lysate). A: NT2D1. 10% SDS PAGE. TA308627 diluted at 1:1000.

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  Homer3 antibody detects Homer3 protein at cytoplasm on Papillary adenocarcinoma by immunohistochemical analysis. Sample: Paraffin-embedded Papillary adenocarcinoma. Homer3 antibody (TA308627) dilution: 1:250.

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  Immunofluorescence analysis of methanol-fixed HeLa, using Homer3 (TA308627) antibody at 1:500 dilution.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 55 and 305 of Homer3 (Uniprot ID#Q9NSC5)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 40 kDa
• Gene Name: homer scaffolding protein 3
• Database Link:
  NP_001139196
  Entrez Gene 26558 MouseEntrez Gene 29548 RatEntrez Gene 9454 Human
  UniProt ID Q9NSC5
• Background: This gene encodes a member of the HOMER family of postsynaptic density scaffolding proteins that share a similar domain structure consisting of an N-terminal Enabled/vasodilator-stimulated phosphoprotein homology 1 domain which mediates protein-protein interactions, and a carboxy-terminal coiled-coil domain and two leucine zipper motifs that are involved in self-oligomerization. The encoded protein binds numerous other proteins including group I metabotropic glutamate receptors, inositol 1,4,5-trisphosphate receptors and amyloid precursor proteins and has been implicated in diverse biological functions such as neuronal signaling, T-cell activation and trafficking of amyloid beta peptides. Alternative splicing results in multiple transcript variants.
• Synonyms: HOMER-3; VESL3
• Note: Seq homology of immunogen across species: Mouse (85%), Rat (86%)

Reference Data

• Protein Families: Druggable Genome