NAT2 Rabbit Polyclonal Antibody

CAT#: TA308634

Rabbit Polyclonal antibody to NAT2 (N-acetyltransferase 2 (arylamine N-acetyltransferase))

Product Images

Sample (30 ug of whole cell lysate). A: A431. B: H1299. 12% SDS PAGE. TA308634 diluted at 1:1000.

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  Immunohistochemical analysis of paraffin-embedded A549 xenograft, using NAT2 (TA308634) antibody at 1:100 dilution.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: IHC:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 198 of NAT2 (Uniprot ID#P11245)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 34 kDa
• Gene Name: N-acetyltransferase 2 (arylamine N-acetyltransferase)
• Database Link:
  NP_000006
  Entrez Gene 704357 MonkeyEntrez Gene 10 Human
  UniProt ID P11245
• Background: This gene encodes an enzyme that functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. Polymorphisms in this gene are responsible for the N-acetylation polymorphism in which human populations segregate into rapid, intermediate, and slow acetylator phenotypes. Polymorphisms in this gene are also associated with higher incidences of cancer and drug toxicity. A second arylamine N-acetyltransferase gene (NAT1) is located near this gene (NAT2). [provided by RefSeq]
• Synonyms: AAC2; NAT-2; PNAT
• Note: Seq homology of immunogen across species: Monkey (91%)

Reference Data

• Protein Families: Transmembrane
• Protein Pathways: Caffeine metabolism, Drug metabolism - other enzymes, Metabolic pathways