WNT10A Rabbit Polyclonal Antibody

CAT#: TA308635

Rabbit polyclonal antibody to WNT10A (wingless-type MMTV integration site family, member 10A)

Product Images

Sample (30 ug of whole cell lysate). A: Raji. 10% SDS PAGE. TA308635 diluted at 1:1000.

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  WNT10A antibody [N1C1-2] detects WNT10A protein at cytoplasm by immunofluorescent analysis. Sample: SKNSH cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: WNT10A protein stained by WNT10A antibody [N1C1-2] (TA308635) diluted at 1:500. Blue

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: ICC/IF:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 47 and 271 of WNT10A (Uniprot ID#Q9GZT5)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 46 kDa
• Gene Name: Wnt family member 10A
• Database Link:
  NP_079492
  Entrez Gene 22409 MouseEntrez Gene 316527 RatEntrez Gene 80326 Human
  UniProt ID Q9GZT5
• Background: The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is strongly expressed in the cell lines of promyelocytic leukemia and Burkitt's lymphoma. In addition, it and another family member, the WNT6 gene, are strongly coexpressed in colorectal cancer cell lines. The gene overexpression may play key roles in carcinogenesis through activation of the WNT-beta-catenin-TCF signaling pathway. This gene and the WNT6 gene are clustered in the chromosome 2q35 region. [provided by RefSeq]
• Synonyms: OODD; SSPS; STHAG4
• Note: Seq homology of immunogen across species: Mouse (96%), Rat (97%), Bovine (96%)

Reference Data

• Protein Families: Secreted Protein, Transmembrane
• Protein Pathways: Basal cell carcinoma, Hedgehog signaling pathway, Melanogenesis, Pathways in cancer, Wnt signaling pathway