PLA2G12A Rabbit Polyclonal Antibody

CAT#: TA308641

Rabbit polyclonal antibody to Phospholipase A2 XIIA (phospholipase A2, group XIIA)

Product Images

Sample (30 ug of whole cell lysate). A: H1299. B: Hela. 12% SDS PAGE. TA308641 diluted at 1:1000.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB:1:500-1:3000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region within amino acids 22 and 115 of PLA2G12A (Uniprot ID#Q9BZM1)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 21 kDa
• Gene Name: phospholipase A2 group XIIA
• Database Link:
  NP_110448
  Entrez Gene 66350 MouseEntrez Gene 362039 RatEntrez Gene 81579 Human
  UniProt ID Q9BZM1
• Background: Secreted phospholipase A2 (sPLA2) enzymes liberate arachidonic acid from phospholipids for production of eicosanoids and exert a variety of physiologic and pathologic effects. Group XII sPLA2s, such as PLA2G12A, have relatively low specific activity and are structurally and functionally distinct from other sPLA2s (Gelb et al., 2000 [PubMed 11031251]). [supplied by OMIM]
• Synonyms: GXII; PLA2G12; ROSSY
• Note: Seq homology of immunogen across species: Mouse (93%), Rat (93%), Rhesus Monkey (100%), Bovine (100%)

Reference Data

• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: alpha-Linolenic acid metabolism, Arachidonic acid metabolism, Ether lipid metabolism, Fc epsilon RI signaling pathway, Glycerophospholipid metabolism, GnRH signaling pathway, Linoleic acid metabolism, Long-term depression, MAPK signaling pathway, Metabolic pathways, Vascular smooth muscle contraction, VEGF signaling pathway