TGF beta Receptor III (TGFBR3) Rabbit Polyclonal Antibody

CAT#: TA308670

Rabbit polyclonal antibody to TGF beta Receptor III (transforming growth factor, beta receptor III)

Product Images

Sample (30 ug of whole cell lysate). A: THP-1. 7.5% SDS PAGE. TA308670 diluted at 1:1000.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB:1:500-1:3000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 88 and 314 of TGF beta Receptor III (Uniprot ID#Q03167)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 94 kDa
• Gene Name: transforming growth factor beta receptor 3
• Database Link:
  NP_003234
  Entrez Gene 21814 MouseEntrez Gene 7049 Human
  UniProt ID Q03167
• Background: Transforming growth factor (TGF)-beta is a multifunctional cytokine that modulates several tissue development and repair processes, including cell differentiation, cell cycle progression, cellular migration, adhesion, and extracellular matrix production. Three TGF-beta forms are encoded by separate genes: TGFB1 (MIM 190180), TGFB2 (MIM 190220), and TGFB3 (MIM 190230). The diverse effects of TGF-beta are mediated by the TGF-beta receptors and cell surface-binding proteins. Three TGF-beta receptors exist: type I (TGFBR1; MIM 190181), type II (TFGBR2; MIM 190182), and type III (TGFBR3). TGFBR3 is a glycoprotein that binds TGFB and exists in both a membrane-bound and a soluble form (Johnson et al., 1995 [PubMed 8530052]). [supplied by OMIM]
• Synonyms: betaglycan; BGCAN
• Note: Seq homology of immunogen across species: Mouse (87%), Pig (89%)

Reference Data

• Protein Families: Druggable Genome, Secreted Protein, Transmembrane