CACNA1B Rabbit Polyclonal Antibody

CAT#: TA308673

Rabbit polyclonal antibody to CACNA1B (calcium channel, voltage-dependent, N type, alpha 1B subunit)

Product Images

CACNA1B antibody [C3], C-term detects CACNA1B protein by Western blot analysis. A. 30 ug U87-MG whole cell lysate/extract. 5 % SDS-PAGE. CACNA1B antibody [C3], C-term (TA308673) dilution: 1:500

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  Immunofluorescence analysis of methanol-fixed A549, using CACNA1B (TA308673) antibody at 1:500 dilution.

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  Figure from citation: Immunoprecipitation of CACNA1B (Cav2.2) protein level by using anti-CACNA1B antibody in rat dorsal root ganglia. View Citation

Specifications

Product Data

• Applications: IF, IP, WB
• Recommended Dilution: ICC/IF:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 2013 and 2209 of CACNA1B (Uniprot ID#Q00975)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Purification: Purified by antigen-affinity chromatography.
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 263 kDa
• Gene Name: calcium voltage-gated channel subunit alpha1 B
• Database Link:
  NP_000709
  Entrez Gene 774 Human
• Background: Voltage-dependent Ca(2+) channels are multisubunit complexes found in the membrane of many excitable cells that regulate calcium entry (see MIM 601011). N-type calcium channels, which control neurotransmitter release from neurons, are dihydropyridine-insensitive and omega-conotoxin-sensitive. The alpha-1 subunit forms the pore through which calcium enters the cell, and is encoded by a family of at least 5 genes. [supplied by OMIM]
• Synonyms: BIII; CACNL1A5; CACNN; Cav2.2

Reference Data

• Protein Families: Druggable Genome, Ion Channels: Calcium, Transmembrane
• Protein Pathways: Calcium signaling pathway, MAPK signaling pathway, Taste transduction, Type II diabetes mellitus