CLIC3 Rabbit Polyclonal Antibody

CAT#: TA308675

Rabbit polyclonal antibody to CLIC3 (chloride intracellular channel 3)

Product Images

Sample (30 ug of whole cell lysate). A:HeLa S3. 12% SDS PAGE. TA308675 diluted at 1:500

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  Immunohistochemical analysis of paraffin-embedded T (IV) (lung CA), using CLIC3 (TA308675) antibody at 1:100 dilution.

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  Immunohistochemical analysis of paraffin-embedded Ca922 xenograft, using CLIC3 (TA308675) antibody at 1:100 dilution.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: IHC:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 236 of CLIC3 (Uniprot ID#O95833)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 27 kDa
• Gene Name: chloride intracellular channel 3
• Database Link:
  NP_004660
  Entrez Gene 69454 MouseEntrez Gene 296566 RatEntrez Gene 9022 Human
  UniProt ID O95833
• Background: Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 3 is a member of the p64 family and is predominantly localized in the nucleus and stimulates chloride ion channel activity. In addition, this protein may participate in cellular growth control, based on its association with ERK7, a member of the MAP kinase family. [provided by RefSeq]
• Synonyms: chloride intracellular channel 3; OTTHUMP00000022630
• Note: Seq homology of immunogen across species: Mouse (89%), Rat (88%), Bovine (90%)

Reference Data

• Protein Families: Druggable Genome, Ion Channels: Other