Calpain 5 (CAPN5) Rabbit Polyclonal Antibody

CAT#: TA308682

Rabbit polyclonal antibody to Calpain-5 (calpain 5)

Product Images

Sample (30 ug of whole cell lysate). A: A431. B: H1299. 7.5% SDS PAGE. Calpain-5 antibody. TA308682 diluted at 1:1000.

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  Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using Calpain-5 (TA308682) antibody at 1:100 dilution.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: ICC/IF:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 381 of Calpain-5 (Uniprot ID#O15484)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 73 kDa
• Gene Name: calpain 5
• Database Link:
  NP_004046
  Entrez Gene 12337 MouseEntrez Gene 171495 RatEntrez Gene 726 Human
  UniProt ID O15484
• Background: Calpains are calcium-dependent cysteine proteases involved in signal transduction in a variety of cellular processes. A functional calpain protein consists of an invariant small subunit and 1 of a family of large subunits. CAPN5 is one of the large subunits. Unlike some of the calpains, CAPN5 and CAPN6 lack a calmodulin-like domain IV. Because of the significant similarity to Caenorhabditis elegans sex determination gene tra-3, CAPN5 is also called as HTRA3. [provided by RefSeq]
• Synonyms: ADNIV; HTRA3; nCL-3; VRNI
• Note: Seq homology of immunogen across species: Mouse (93%), Rat (90%), Xenopus laevis (81%), Bovine (95%)

Reference Data

• Protein Families: Druggable Genome, Protease