PDE9A Rabbit Polyclonal Antibody

CAT#: TA308688

Rabbit Polyclonal antibody to PDE9A (phosphodiesterase 9A)

Product Images

Sample (50 ug of whole cell lysate). A: Mouse brain. 7.5% SDS PAGE. TA308688 diluted at 1:1000.

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  Sample (30 ug of whole cell lysate). A: 293T. 7.5% SDS PAGE. TA308688 diluted at 1:3000

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  Immunohistochemical analysis of paraffin-embedded N87 xenograft, using PDE9A (TA308688) antibody at 1:500 dilution.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: IHC:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 216 of PDE9A (Uniprot ID#O76083)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 69 kDa
• Gene Name: phosphodiesterase 9A
• Database Link:
  NP_001001585
  Entrez Gene 18585 MouseEntrez Gene 191569 RatEntrez Gene 5152 Human
  UniProt ID O76083
• Background: The protein encoded by this gene catalyzes the hydrolysis of cAMP and cGMP to their corresponding monophosphates. The encoded protein plays a role in signal transduction by regulating the intracellular concentration of these cyclic nucleotides. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq]
• Synonyms: HSPDE9A2
• Note: Seq homology of immunogen across species: Rat (96%)

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Progesterone-mediated oocyte maturation, Purine metabolism