CTBP1 Rabbit Polyclonal Antibody

CAT#: TA308690

Rabbit polyclonal antibody to CtBP1 (C-terminal binding protein 1)

Product Images

Sample (30 ug of whole cell lysate). A: Hela. 10% SDS PAGE. TA308690 diluted at 1:1000.

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  Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using CtBP1 (TA308690) antibody at 1:200 dilution.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: ICC/IF:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment corresponding to a region within amino acids 194 and 379 of CtBP1 (Uniprot ID#Q13363)
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 48 kDa
• Gene Name: C-terminal binding protein 1
• Database Link:
  NP_001012632
  Entrez Gene 13016 MouseEntrez Gene 29382 RatEntrez Gene 1487 Human
  UniProt ID Q13363
• Background: This gene encodes a protein that binds to the C-terminus of adenovirus E1A proteins. This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation. This protein and the product of a second closely related gene, CTBP2, can dimerize. Both proteins can also interact with a polycomb group protein complex which participates in regulation of gene expression during development. Alternative splicing of transcripts from this gene results in multiple transcript variants. [provided by RefSeq]
• Synonyms: BARS
• Note: Seq homology of immunogen across species: Mouse (100%), Rat (100%), Rhesus Monkey (100%)

Reference Data

• Protein Pathways: Chronic myeloid leukemia, Notch signaling pathway, Pathways in cancer, Wnt signaling pathway