Natriuretic Peptide Receptor C (NPR3) Rabbit Polyclonal Antibody

CAT#: TA308692

Rabbit polyclonal antibody to NPR-C (natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C))

Product Images

Sample (30 ug of whole cell lysate). A: Hep G2. 7.5% SDS PAGE. TA308692 diluted at 1:10000

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  NPR-C antibody [N3C3] detects NPR-C protein at cytosol on mouse testis by immunohistochemical analysis. Sample: Paraffin-embedded mouse testis. NPR-C antibody [N3C3] (TA308692) dilution: 1:500.

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  Immunohistochemical analysis of paraffin-embedded U87 xenograft, using NPR-C (TA308692) antibody at 1:500 dilution.

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  NPR-C antibody [N3C3] detects NPR-C protein at cytoplasm by immunofluorescent analysis. Sample: A431 cells were fixed in ice-cold MeOH for 5 min. Green: NPR-C protein stained by NPR-C antibody [N3C3] (TA308692) diluted at 1:500. Blue: Hoechst 33342 staini

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  Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using NPR-C (TA308692) antibody at 1:200 dilution.

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Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:5000-1:20000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 265 and 514 of NPR-C
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 60 kDa
• Gene Name: natriuretic peptide receptor 3
• Database Link:
  NP_000899
  Entrez Gene 25339 RatEntrez Gene 4883 Human
  UniProt ID P17342
• Background: The family of natriuretic peptides (see MIM 108780) elicit a number of vascular, renal, and endocrine effects that are important in the maintenance of blood pressure and extracellular fluid volume. These effects are mediated by specific binding of the peptides to cell surface receptors in the vasculature, kidney, adrenal, and brain. [supplied by OMIM]
• Synonyms: ANP-C; ANPR-C; ANPRC; C5orf23; GUCY2B; NPR-C; NPRC
• Note: Seq homology of immunogen across species: Rat (96%), Xenopus laevis (82%)

Reference Data

• Protein Families: Druggable Genome, Transmembrane